RUNX1

Across TCGA patient cohorts, RUNX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,619 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RUNX1-associated proteins across cancer lineages are PCOLCE, RAI14, and CTHRC1. Each is linked with RUNX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RUNX1-to-partner and partner-to-RUNX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUNX1 versus PCOLCE in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNX1→partner) and Y-score (partner→RUNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+0.865	+1.287	<.001	<.001	3	8
OV	RAI14 →	+0.414	+1.222	<.001	<.001	3	8
CCRCC	CTHRC1 →	+0.881	+0.844	<.001	<.001	3	8
OV	VCAN →	+0.981	+1.259	<.001	<.001	3	7
HNSC	VCAN_S2116 →	+1.199	+0.941	<.001	<.001	3	7
BRCA	VIM →	+0.478	+0.843	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,619 associations by consensus.

RUNX1 vs PCOLCE — OV

Explore this scatter interactively →