RUNX1

Across TCGA patient cohorts, RUNX1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,800 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RUNX1-associated genes across cancer lineages are LGALS1, DSE, and TGFBI. Each is linked with RUNX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RUNX1-to-partner and partner-to-RUNX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUNX1 versus LGALS1 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNX1→partner) and Y-score (partner→RUNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LGALS1 →	+0.962	+0.551	<.001	<.001	3	7
OV	DSE →	+0.917	+0.759	<.001	<.001	3	7
GBM	TGFBI →	+1.871	+0.636	<.001	<.001	3	7
OV	RUNX2 →	+1.268	+0.627	<.001	<.001	3	7
OV	PODNL1 →	+1.366	+0.668	<.001	<.001	3	7
GBM	EMP3 →	+0.822	+0.472	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,800 associations by consensus.

RUNX1 vs LGALS1 — OV

Explore this scatter interactively →