RUNDC3A

Across TCGA patient cohorts, RUNDC3A mutation is significantly associated with the RNA expression of many other genes, with 1,456 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUNDC3A-associated genes across cancer lineages are TTTY12, H3P38, and RNA5SP282. Each is linked with RUNDC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both RUNDC3A-to-partner and partner-to-RUNDC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTTY12 grouped by RUNDC3A-low versus RUNDC3A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC3A→partner) and Y-score (partner→RUNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TTTY12 →	+0.044	+4.812	<.001	.006	3	2
CESC	H3P38 →	+0.146	+4.455	<.001	.005	3	2
SKCM	RNA5SP282 →	+0.373	+3.490	<.001	.008	3	2
UCEC	RNU2-47P →	+0.073	+3.890	<.001	.007	3	2
UCEC	RNU6-693P →	+0.139	+3.219	<.001	.004	3	2
CESC	OR10G3 →	+0.033	+5.569	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,456 associations by consensus.

TTTY12 by RUNDC3A expression — CESC

Explore this box plot interactively →