RUNDC3A

Across TCGA cell cohorts, RUNDC3A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,260 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RUNDC3A-associated GO terms across cancer lineages are Protein sumoylation, Regulation of myoblast fusion, and Negative regulation of mRNA metabolic process. Each is linked with RUNDC3A in more than 11 cancer types. Because this analysis shows association rather than direction, both RUNDC3A-to-partner and partner-to-RUNDC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by RUNDC3A-low versus RUNDC3A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUNDC3A→partner) and Y-score (partner→RUNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein sumoylation →	+0.085	+2.322	.002	.002	2	12
LUNG_SCLC	Regulation of myoblast fusion →	+0.112	+3.120	<.001	<.001	3	9
CNS	Negative regulation of mRNA metabolic process →	+0.030	+0.712	<.001	<.001	3	9
BONE	Positive regulation of double-strand break repair →	+0.066	+0.737	.002	<.001	2	10
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.047	+0.506	<.001	.001	2	10
OESOPHAGUS	Regulation of TORC1 signaling →	+0.058	+0.885	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,260 associations by consensus.

Protein sumoylation by RUNDC3A expression — LUNG_SCLC

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