Across TCGA patient cohorts, RUFY4 mutation is significantly associated with the RNA expression of many other genes, with 1,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RUFY4-associated genes across cancer lineages are CPSF4, PAQR4, and NDUFB6. Each is linked with RUFY4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUFY4-to-partner and partner-to-RUFY4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY4→partner) and Y-score (partner→RUFY4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CPSF4 →	+0.375	+2.332	.003	<.001	3	2
UCEC	PAQR4 →	+0.563	+3.459	.009	<.001	3	2
UCEC	NDUFB6 →	+0.432	+2.233	.002	.005	3	2
UCEC	ZMYND19 →	+0.373	+3.584	.002	.002	3	2
UCEC	ZFYVE19 →	+0.397	+2.828	.001	.001	3	2
UCEC	CIAO2B →	+0.375	+3.470	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,180 associations by consensus.

Exploration

RUFY4 survival (RNA) · tumor vs normal (RNA) · all RUFY4 data types