RUFY3

Across TCGA cell cohorts, RUFY3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RUFY3-associated genes across cancer lineages are SPACA5B, OR2T29, and OR2T10. Each is linked with RUFY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RUFY3-to-partner and partner-to-RUFY3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPACA5B grouped by RUFY3-low versus RUFY3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY3→partner) and Y-score (partner→RUFY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SPACA5B →	+0.657	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR2T29 →	+0.642	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR2T10 →	+0.036	+5.369	<.001	.004	3	1
SOFT_TISSUE	LYZL6 →	+0.019	+5.369	<.001	.004	3	1
STOMACH	GPR101 →	+0.013	+5.285	<.001	.003	3	1
STOMACH	KRTAP9-4 →	+0.040	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SPACA5B by RUFY3 expression — SOFT_TISSUE

Explore this box plot interactively →