RUFY1

Across TCGA patient cohorts, RUFY1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,885 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RUFY1-associated genes across cancer lineages are ERGIC1, ATP6V0E1, and PWWP2A. Each is linked with RUFY1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RUFY1-to-partner and partner-to-RUFY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RUFY1 versus ERGIC1 in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY1→partner) and Y-score (partner→RUFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ERGIC1 →	+0.999	+0.530	<.001	<.001	3	6
OV	ATP6V0E1 →	+0.736	+0.337	<.001	.001	3	6
COAD	PWWP2A →	+0.386	+0.168	<.001	.001	3	6
BRCA	TPRG1 →	+2.207	+0.345	<.001	<.001	3	6
GBM	MR1 →	+0.760	+0.384	<.001	<.001	3	6
LSCC	IL16 →	+0.681	+0.239	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,885 associations by consensus.

RUFY1 vs ERGIC1 — OV

Explore this scatter interactively →