RUFY1

Across TCGA cell cohorts, RUFY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,539 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RUFY1-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Pre-mRNA catabolic process, and Subtelomeric heterochromatin formation. Each is linked with RUFY1 in more than 15 cancer types. Because this analysis shows association rather than direction, both RUFY1-to-partner and partner-to-RUFY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by RUFY1-low versus RUFY1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RUFY1→partner) and Y-score (partner→RUFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of mitotic cytokinesis →	+0.168	+0.636	.002	.002	3	16
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.136	+0.773	<.001	<.001	3	14
LARGE_INTESTINE	Subtelomeric heterochromatin formation →	+0.088	+0.635	<.001	<.001	3	13
BONE	Metaphase/anaphase transition of cell cycle →	+0.142	+0.680	.003	.003	3	13
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.084	+0.777	<.001	<.001	3	13
OVARY	Establishment of RNA localization →	+0.083	+0.783	.002	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,539 associations by consensus.

Positive regulation of mitotic cytokinesis by RUFY1 expression — BREAST

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