RUFY1-AS1

Across TCGA pan-cancer cohorts, RUFY1-AS1 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated RUFY1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RUFY1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RUFY1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, PAAD, and LIHC are the cancer types where RUFY1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.747	0.570	<.001	113	view →
PAAD	OS	Tertile	All	0.591	0.262	<.001	62	view →
LIHC	OS	Tertile	All	0.656	0.852	<.001	46	view →
BRCA	OS	Quartile	III,IV	0.945	0.746	.001	40	view →
LGG	DFS	Tertile	All	0.658	0.820	<.001	40	view →
UVM	DFS	Quartile	III,IV	0.170	0.900	.001	37	view →
UCS	DFS	Tertile	IV	0.956	0.422	.024	24	view →
PRAD	DFS	Tertile	All	0.713	0.833	<.001	18	view →
ACC	OS	Tertile	All	0.639	0.856	.027	18	view →
CHOL	DFS	Median	All	0.727	0.227	.012	15	view →
LUSC	DFS	Tertile	III,IV	0.338	0.935	.007	13	view →
CESC	OS	Median	IV	0.822	0.340	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

RUFY1-AS1–HNSC (OS)

Open the HNSC breakdown →