RTTN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RTTN protein abundance is significantly associated with the RNA expression of many other genes, with 2,361 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RTTN-associated genes across cancer lineages are IL2RB, LSM5, and RPA3. Each is linked with RTTN in more than 1 cancer types. Because this analysis shows association rather than direction, both RTTN-to-partner and partner-to-RTTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTTN versus IL2RB in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTTN→partner) and Y-score (partner→RTTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVIL2RB →-0.758-0.519.009.00232
OVLSM5 →+0.856+0.774<.001<.00132
OVRPA3 →+1.186+0.805<.001.00132
OVTRMT13 →+0.526+0.592.006.00832
OVCDCA5 →+1.255+0.701.001.00832
OVLINC02867 →+0.259+0.604.005.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,361 associations by consensus.

RTTN vs IL2RB — OV

Per-sample scatter of RTTN vs IL2RB in OV (Pearson r = -0.43).

Explore this scatter interactively →

Exploration