RTTN

Across TCGA cell cohorts, RTTN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,439 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTTN-associated GO terms across cancer lineages are Centriole replication, Ciliary basal body organization, and Centrosome duplication. Each is linked with RTTN in more than 18 cancer types. Because this analysis shows association rather than direction, both RTTN-to-partner and partner-to-RTTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole replication grouped by RTTN-low versus RTTN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTTN→partner) and Y-score (partner→RTTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Centriole replication →	+0.155	+0.821	.001	.002	3	19
LARGE_INTESTINE	Ciliary basal body organization →	+1.058	+0.981	<.001	<.001	3	17
BONE	Centrosome duplication →	+0.130	+0.755	<.001	<.001	3	16
OESOPHAGUS	Centrosome cycle →	+0.129	+0.966	<.001	<.001	3	16
LUNG_SCLC	Centriole-centriole cohesion →	+0.125	+1.147	<.001	<.001	3	16
BONE	Centriole assembly →	+0.134	+0.927	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,439 associations by consensus.

Centriole replication by RTTN expression — BONE

Explore this box plot interactively →