RTRAF

Across TCGA cell cohorts, RTRAF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,738 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTRAF-associated GO terms across cancer lineages are Mitochondrial tRNA methylation, Protein farnesylation, and Monoubiquitinated protein deubiquitination. Each is linked with RTRAF in more than 10 cancer types. Because this analysis shows association rather than direction, both RTRAF-to-partner and partner-to-RTRAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial tRNA methylation grouped by RTRAF-low versus RTRAF-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTRAF→partner) and Y-score (partner→RTRAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial tRNA methylation →	+0.109	+0.659	.003	.006	3	11
OESOPHAGUS	Protein farnesylation →	+0.139	+0.758	<.001	<.001	3	9
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.166	+0.610	.001	.007	3	9
UPPER_AERODIGESTIVE_TRACT	Oxidative RNA demethylation →	+0.097	+0.830	.004	<.001	3	9
CNS	Response to manganese-induced endoplasmic reticulum stress →	+0.050	+0.392	<.001	.006	3	8
CNS	Spliceosome-depend formation of circular RNA →	+0.147	+0.795	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,738 associations by consensus.

Mitochondrial tRNA methylation by RTRAF expression — BONE

Explore this box plot interactively →