Across TCGA patient cohorts, RTP5 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTP5-associated genes across cancer lineages are EGFR_pY1068, p62 Lck ligand, and Di-Ras3. Each is linked with RTP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTP5-to-partner and partner-to-RTP5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP5→partner) and Y-score (partner→RTP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.196	-1.584	.046	.036	3	2
UCEC	p62 Lck ligand →	+0.379	+2.000	.002	.010	3	2
UCEC	Di-Ras3 →	-0.153	-3.308	.008	.009	3	2
UCEC	A-Raf_pS299 →	-0.100	-2.321	.033	.034	3	1
UCEC	Fibronectin →	-0.322	-2.502	.012	.002	3	1
UCEC	FOXO3a_pS318_S321 →	-0.116	-1.990	.017	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

RTP5 survival (RNA) · tumor vs normal (RNA) · all RTP5 data types