RTP3

Across TCGA patient cohorts, RTP3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTP3-associated genes across cancer lineages are Megakaryocytes and Class-switched memory B-cells. Each is linked with RTP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTP3-to-partner and partner-to-RTP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocytes grouped by RTP3-low versus RTP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP3→partner) and Y-score (partner→RTP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Megakaryocytes →	+0.035	+2.850	.018	.035	3	1
SKCM	Class-switched memory B-cells →	-0.046	-2.453	.030	.020	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Megakaryocytes by RTP3 expression — UCEC

Explore this box plot interactively →