Across TCGA patient cohorts, RTP2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTP2-associated genes across cancer lineages are Annexin-1, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with RTP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTP2-to-partner and partner-to-RTP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP2→partner) and Y-score (partner→RTP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.693	+3.019	.004	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+0.754	+2.189	.006	.034	3	2
UCEC	Cyclin-B1 →	+0.616	+2.584	.018	.011	3	2
UCEC	A-Raf_pS299 →	-0.137	-2.999	.013	.035	3	1
UCEC	Ku80 →	+0.280	+1.887	.011	.031	3	1
UCEC	Notch1 →	+0.180	+3.013	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

RTP2 survival (RNA) · tumor vs normal (RNA) · all RTP2 data types