RTP1

Across TCGA cell cohorts, RTP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 447 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RTP1-associated GO terms across cancer lineages are Regulatory ncRNA-mediated gene silencing, Termination of RNA polymerase II transcription, and ATP metabolic process. Each is linked with RTP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RTP1-to-partner and partner-to-RTP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulatory ncRNA-mediated gene silencing grouped by RTP1-low versus RTP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTP1→partner) and Y-score (partner→RTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulatory ncRNA-mediated gene silencing →	+0.059	+0.330	.001	.004	3	4
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.098	+0.594	.003	.005	3	4
PANCREAS	ATP metabolic process →	+0.064	+0.012	.001	.003	3	4
LUNG_SCLC	Organelle transport along microtubule →	+0.050	+0.329	.001	.004	3	3
LUNG_SCLC	Transport along microtubule →	+0.046	+0.346	.001	.002	3	3
LUNG_SCLC	mRNA transport →	+0.063	+0.325	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

Regulatory ncRNA-mediated gene silencing by RTP1 expression — LUNG_SCLC

Explore this box plot interactively →