RTN4RL2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RTN4RL2 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTN4RL2-associated genes across cancer lineages are ZDHHC20P2, RNA5SP386, and AKR1B10P2. Each is linked with RTN4RL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN4RL2-to-partner and partner-to-RTN4RL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN4RL2→partner) and Y-score (partner→RTN4RL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCZDHHC20P2 →+0.133+5.669<.001.00332
SKCMRNA5SP386 →+0.488+5.351<.001.00132
CESCAKR1B10P2 →+0.041+6.144<.001.00132
UCECSSX6P →+0.203+3.877.002.00431
BLCAMIR4450 →+0.729+5.588<.001.00431
BLCARN7SL366P →+0.200+6.618<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration