RTN4R

Across TCGA pan-cancer cohorts, RTN4R Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RTN4R data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RTN4R Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RTN4R expression acts as an unfavorable survival marker.

PAAD, ACC, and LUAD are the cancer types where RTN4R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	II,III,IV	0.146	0.557	<.001	24	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →
LUAD	DFS	Median	All	0.254	0.815	<.001	6	view →
LIHC	OS	Median	II,III,IV	0.239	0.715	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RTN4R–PAAD (OS)

Open the PAAD breakdown →