RTN4IP1

Across TCGA pan-cancer cohorts, RTN4IP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RTN4IP1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RTN4IP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RTN4IP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, HNSC, and CCRCC are the cancer types where RTN4IP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.910	.011	84	view →
HNSC	DFS	Quartile	All	0.883	1.000	.002	27	view →
CCRCC	OS	Median	All	0.984	0.903	.026	4	view →
PDAC	OS	Median	All	0.925	0.726	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RTN4IP1–COAD (DFS)

Open the COAD breakdown →