RTN4IP1

Across TCGA patient cohorts, RTN4IP1 mutation is significantly associated with the RNA expression of many other genes, with 2,013 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTN4IP1-associated genes across cancer lineages are PSAT1P4, H3P29, and FARSBP1. Each is linked with RTN4IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTN4IP1-to-partner and partner-to-RTN4IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by RTN4IP1-low versus RTN4IP1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN4IP1→partner) and Y-score (partner→RTN4IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	PSAT1P4 →	+0.067	+5.038	.003	.009	3	2
BLCA	H3P29 →	+0.247	+5.685	<.001	.003	3	2
BLCA	FARSBP1 →	+0.020	+5.106	.001	.008	3	2
BLCA	RNU6-1150P →	+0.694	+5.251	<.001	.006	3	2
HNSC	MIR6799 →	+0.837	+5.822	<.001	.003	3	2
UCEC	HMGB1P49 →	+0.250	+2.929	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,013 associations by consensus.

PSAT1P4 by RTN4IP1 expression — BLCA

Explore this box plot interactively →