RTN4

Across TCGA cell cohorts, RTN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,637 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RTN4-associated GO terms across cancer lineages are PML body organization, Cellular response to abiotic stimulus, and Cellular response to environmental stimulus. Each is linked with RTN4 in more than 15 cancer types. Because this analysis shows association rather than direction, both RTN4-to-partner and partner-to-RTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by RTN4-low versus RTN4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN4→partner) and Y-score (partner→RTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	PML body organization →	+0.240	+1.103	<.001	<.001	3	15
LIVER	Cellular response to abiotic stimulus →	+0.044	+0.878	.001	.001	2	16
LIVER	Cellular response to environmental stimulus →	+0.044	+0.878	.001	.001	2	16
BONE	Regulation of proteolysis →	+0.112	+1.401	<.001	<.001	3	14
BONE	Vesicle cargo loading →	+0.130	+1.839	<.001	<.001	3	14
BONE	Positive regulation of cell-substrate junction organization →	+0.165	+1.256	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,637 associations by consensus.

PML body organization by RTN4 expression — LIVER

Explore this box plot interactively →