RTN3

Across TCGA cell cohorts, RTN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,872 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RTN3-associated GO terms across cancer lineages are Endoplasmic reticulum tubular network formation, Post-Golgi vesicle-mediated transport, and Protein exit from endoplasmic reticulum. Each is linked with RTN3 in more than 12 cancer types. Because this analysis shows association rather than direction, both RTN3-to-partner and partner-to-RTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum tubular network formation grouped by RTN3-low versus RTN3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN3→partner) and Y-score (partner→RTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Endoplasmic reticulum tubular network formation →	+0.127	+1.002	<.001	<.001	3	13
SOFT_TISSUE	Post-Golgi vesicle-mediated transport →	+0.043	+0.600	<.001	.009	3	9
LARGE_INTESTINE	Protein exit from endoplasmic reticulum →	+0.104	+0.635	.002	.001	3	9
LUNG_SCLC	Positive regulation of attachment of spindle microtubules to kinetochore →	+0.152	+0.927	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.053	+0.650	.003	.004	3	8
LARGE_INTESTINE	Endoplasmic reticulum to cytosol transport →	+0.110	+0.638	.002	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,872 associations by consensus.

Endoplasmic reticulum tubular network formation by RTN3 expression — PANCREAS

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