RTN2

Across TCGA cell cohorts, RTN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,155 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTN2-associated GO terms across cancer lineages are AMPA glutamate receptor clustering, Glutamate receptor clustering, and Organelle membrane fusion. Each is linked with RTN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RTN2-to-partner and partner-to-RTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMPA glutamate receptor clustering grouped by RTN2-low versus RTN2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTN2→partner) and Y-score (partner→RTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	AMPA glutamate receptor clustering →	+1.609	+1.728	<.001	<.001	3	9
OESOPHAGUS	Glutamate receptor clustering →	+1.609	+1.728	<.001	<.001	3	9
STOMACH	Organelle membrane fusion →	+0.071	+1.439	<.001	<.001	3	8
LIVER	Cytokinesis →	+0.054	+1.327	.006	.003	3	8
OVARY	Adult locomotory behavior →	+0.118	+1.151	.001	<.001	3	8
STOMACH	Negative regulation of calcium ion export across plasma membrane →	+0.076	+1.645	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,155 associations by consensus.

AMPA glutamate receptor clustering by RTN2 expression — OESOPHAGUS

Explore this box plot interactively →