RTL9

Across TCGA cell cohorts, RTL9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,185 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RTL9-associated GO terms across cancer lineages are Regulation of ubiquitin-dependent protein catabolic process, Positive regulation of ferroptosis, and Regulation of protein localization to mitochondrion. Each is linked with RTL9 in more than 8 cancer types. Because this analysis shows association rather than direction, both RTL9-to-partner and partner-to-RTL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ubiquitin-dependent protein catabolic process grouped by RTL9-low versus RTL9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL9→partner) and Y-score (partner→RTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of ubiquitin-dependent protein catabolic process →	+0.038	+0.069	.002	.009	3	8
BLOOD_Lymphoma	Positive regulation of ferroptosis →	+0.083	+0.112	.004	.005	3	8
LUNG_NSCLC_LUSC	Regulation of protein localization to mitochondrion →	+0.104	+0.088	.004	.006	2	9
BLOOD_Lymphoma	Regulation of translational initiation →	+0.085	+0.163	<.001	.001	3	8
LUNG_SCLC	Regulation of RNA splicing →	+0.077	+0.317	<.001	<.001	2	9
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.097	+0.101	<.001	.007	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,185 associations by consensus.

Regulation of ubiquitin-dependent protein catabolic process by RTL9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →