RTL9

Across TCGA cell cohorts, RTL9 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RTL9-associated genes across cancer lineages are ZPBP2, OR10G2, and H2BC1. Each is linked with RTL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL9-to-partner and partner-to-RTL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZPBP2 grouped by RTL9-low versus RTL9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL9→partner) and Y-score (partner→RTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZPBP2 →	+0.509	+4.099	<.001	.001	3	2
SKIN	OR10G2 →	+0.014	+4.437	<.001	.004	3	2
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1
SOFT_TISSUE	OR11H12 →	+0.058	+4.222	<.001	.007	3	1
LUNG_SCLC	BTNL3 →	+0.067	+3.440	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

ZPBP2 by RTL9 expression — BLOOD_Leukemia

Explore this box plot interactively →