Across TCGA cell cohorts, RTL8B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,580 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RTL8B-associated GO terms across cancer lineages are Response to L-glutamate, Positive regulation of actin filament bundle assembly, and Positive regulation of cell-substrate junction organization. Each is linked with RTL8B in more than 10 cancer types. Because this analysis shows association rather than direction, both RTL8B-to-partner and partner-to-RTL8B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL8B→partner) and Y-score (partner→RTL8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to L-glutamate →	+0.208	+1.976	.004	.002	3	11
CNS	Positive regulation of actin filament bundle assembly →	+0.093	+1.038	<.001	.006	3	11
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.138	+1.509	<.001	.007	3	10
SOFT_TISSUE	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.076	+1.699	<.001	.002	3	10
BLOOD_Lymphoma	Protein insertion into ER membrane →	+0.102	+0.061	<.001	<.001	3	9
LUNG_SCLC	Regulation of ubiquitin-protein transferase activity →	+0.125	+1.310	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,580 associations by consensus.

Exploration

RTL8B survival (RNA) · tumor vs normal (RNA) · all RTL8B data types