Across TCGA pan-cancer cohorts, RTL8A Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RTL8A data layer compared with 26 for mass-spec protein and 1 for mass-spec protein.
The strongest signal is observed in thymoma (THYM), where higher RTL8A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RTL8A expression acts as an unfavorable survival marker.
THYM, LIHC, and LUSC are the cancer types where RTL8A Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.