Across TCGA patient cohorts, RTL8A protein abundance is significantly associated with the RNA expression of many other genes, with 2,656 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RTL8A-associated genes across cancer lineages are CCDC160, NFKB1, and CDKAL1. Each is linked with RTL8A in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL8A-to-partner and partner-to-RTL8A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL8A→partner) and Y-score (partner→RTL8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCDC160 →	-1.779	-0.784	<.001	<.001	3	2
HNSC	NFKB1 →	-0.718	-1.111	.001	.002	3	2
GBM	CDKAL1 →	+0.556	+1.002	.004	.003	3	2
GBM	NAIPP4 →	+0.952	+1.002	.001	.003	3	2
BRCA	KCNE4 →	-2.407	-0.757	<.001	<.001	3	2
GBM	JAGN1 →	+0.716	+1.473	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,656 associations by consensus.

Exploration

RTL8A survival (RNA) · tumor vs normal (RNA) · all RTL8A data types