Across TCGA patient cohorts, RTL6 mutation is significantly associated with the RNA expression of many other genes, with 751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTL6-associated genes across cancer lineages are PRELID1P2, CDC45, and RN7SL453P. Each is linked with RTL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL6-to-partner and partner-to-RTL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL6→partner) and Y-score (partner→RTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	PRELID1P2 →	+0.148	+3.464	<.001	.005	3	2
UCEC	CDC45 →	+0.689	+3.475	.005	.002	3	2
SKCM	RN7SL453P →	+0.063	+4.212	<.001	.007	3	2
BRCA	MIR4441 →	+0.346	+5.096	.003	.008	3	2
SKCM	RPS7P13 →	+0.108	+4.037	<.001	<.001	3	2
BRCA	RNA5SP158 →	+0.312	+6.215	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 751 associations by consensus.

Exploration

RTL6 survival (RNA) · tumor vs normal (RNA) · all RTL6 data types