Across TCGA cell cohorts, RTL6 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTL6-associated genes across cancer lineages are LYZL2, OR13H1, and C14orf177. Each is linked with RTL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTL6-to-partner and partner-to-RTL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL6→partner) and Y-score (partner→RTL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LYZL2 →	+0.025	+5.569	<.001	.001	3	1
BLOOD_Leukemia	OR13H1 →	+0.145	+5.060	<.001	.001	3	1
BLOOD_Leukemia	C14orf177 →	+0.063	+5.507	<.001	<.001	3	1
BLOOD_Leukemia	TEX43 →	+0.105	+4.969	<.001	.003	3	1
BLOOD_Leukemia	CSHL1 →	+0.026	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR6C3 →	+0.027	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

RTL6 survival (RNA) · tumor vs normal (RNA) · all RTL6 data types