RTL4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RTL4 mutation is significantly associated with the RNA expression of many other genes, with 4,150 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RTL4-associated genes across cancer lineages are UBAC1, PIN1, and CXXC1. Each is linked with RTL4 in more than 3 cancer types. Because this analysis shows association rather than direction, both RTL4-to-partner and partner-to-RTL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL4→partner) and Y-score (partner→RTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUBAC1 →+0.310+1.903.001<.00134
UCECPIN1 →+0.345+2.687.002<.00133
UCECCXXC1 →+0.343+4.087.001<.00133
UCECMRTO4 →+0.435+2.632<.001<.00133
UCECMYL12BP1 →+0.459+1.860<.001<.00133
LUSCRNA5SP57 →+0.160+3.326.001.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,150 associations by consensus.

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