Across TCGA cell cohorts, RTL4 mutation is significantly associated with the mutation status of many other genes, with 187 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RTL4-associated genes across cancer lineages are KRTAP10-7, KCNA4, and ACCSL. Each is linked with RTL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both RTL4-to-partner and partner-to-RTL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTL4→partner) and Y-score (partner→RTL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-7 →	+4.339	+4.339	.009	.009	1	3
LUNG_SCLC	KCNA4 →	+3.307	+3.777	.005	.005	1	3
LARGE_INTESTINE	ACCSL →	+4.672	+5.329	<.001	<.001	1	2
LARGE_INTESTINE	FAM187A →	+5.087	+4.523	.006	.006	1	2
LUNG_SCLC	TLR7 →	+5.307	+4.651	<.001	<.001	1	2
STOMACH	SORCS1 →	+3.942	+4.584	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

Exploration

RTL4 survival (RNA) · tumor vs normal (RNA) · all RTL4 data types