Across TCGA pan-cancer cohorts, RTL10 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RTL10 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher RTL10 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated RTL10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KICH, LIHC, and SKCM are the cancer types where RTL10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
LIHC	DFS	Median	All	0.125	0.545	.003	12	view →
SKCM	OS	Median	All	0.179	0.781	<.001	9	view →
UCEC	DFS	Median	All	1.000	0.630	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RTL10 tumor-vs-normal RNA expression · all RTL10 data types