Across TCGA pan-cancer cohorts, RTL10 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RTL10 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RTL10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RTL10 expression acts as an unfavorable survival marker.

GBM and LUAD are the cancer types where RTL10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.207	0.769	.024	16	view →
LUAD	DFS	Median	All	0.845	1.000	.005	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: RTL10 tumor-vs-normal RNA expression · all RTL10 data types