RTKN2

Across TCGA cell cohorts, RTKN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,354 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTKN2-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Negative regulation of cell cycle process, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with RTKN2 in more than 16 cancer types. Because this analysis shows association rather than direction, both RTKN2-to-partner and partner-to-RTKN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by RTKN2-low versus RTKN2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTKN2→partner) and Y-score (partner→RTKN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.109	+1.284	.002	.004	3	17
BONE	Negative regulation of cell cycle process →	+0.056	+0.792	.002	.001	3	14
LIVER	Regulation of metaphase/anaphase transition of cell cycle →	+0.111	+1.416	<.001	.001	3	13
OESOPHAGUS	Replication fork processing →	+0.099	+1.795	.005	<.001	3	13
LARGE_INTESTINE	Negative regulation of mitotic nuclear division →	+0.095	+0.994	<.001	<.001	3	13
SKIN	Regulation of meiosis I →	+0.128	+0.860	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,354 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by RTKN2 expression — LIVER

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