RTF1

Across TCGA cell cohorts, RTF1 mutation is significantly associated with the drug of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RTF1-associated genes across cancer lineages are Zoledronate, Oxaliplatin, and 743380. Each is linked with RTF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RTF1-to-partner and partner-to-RTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zoledronate grouped by RTF1-low versus RTF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTF1→partner) and Y-score (partner→RTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Zoledronate →	+0.303	+2.649	.031	.046	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.599	+2.649	.023	.046	3	1
LARGE_INTESTINE	743380 →	+0.747	+2.649	.005	.046	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.714	+2.652	.028	.045	3	1
LARGE_INTESTINE	IC-87114 →	+0.244	+2.684	.017	.035	3	1
LARGE_INTESTINE	CP466722 →	+0.409	+2.652	.039	.045	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Zoledronate by RTF1 expression — LARGE_INTESTINE

Explore this box plot interactively →