RTEL1

Across TCGA patient cohorts, RTEL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,690 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RTEL1-associated proteins across cancer lineages are RTF2, TAF4, and MRGBP. Each is linked with RTEL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RTEL1-to-partner and partner-to-RTEL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTEL1 versus RTF2 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RTEL1→partner) and Y-score (partner→RTEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RTF2 →	+0.383	+0.431	<.001	<.001	3	5
BRCA	TAF4 →	+0.259	+0.333	<.001	<.001	3	4
BRCA	MRGBP →	+0.331	+0.213	.006	.001	3	4
LSCC	YTHDF1 →	+0.310	+0.356	<.001	<.001	3	4
GBM	CTNNBL1 →	+0.316	+0.350	<.001	.001	3	4
LSCC	DGKA →	-0.264	-0.253	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,690 associations by consensus.

RTEL1 vs RTF2 — GBM

Explore this scatter interactively →