RTCB

Across TCGA cell cohorts, RTCB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,259 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RTCB-associated GO terms across cancer lineages are Mitotic spindle elongation, Mitotic spindle midzone assembly, and Positive regulation of mitochondrial fusion. Each is linked with RTCB in more than 13 cancer types. Because this analysis shows association rather than direction, both RTCB-to-partner and partner-to-RTCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by RTCB-low versus RTCB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTCB→partner) and Y-score (partner→RTCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic spindle elongation →	+0.234	+0.576	.007	.002	3	14
BONE	Mitotic spindle midzone assembly →	+0.234	+0.576	.007	.002	3	14
OVARY	Positive regulation of mitochondrial fusion →	+0.162	+0.641	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	P-body assembly →	+0.132	+0.928	<.001	<.001	3	12
SKIN	rRNA 5'-end processing →	+0.099	+0.780	<.001	<.001	3	12
SKIN	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.099	+0.780	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,259 associations by consensus.

Mitotic spindle elongation by RTCB expression — BONE

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