RTCA

Across TCGA cell cohorts, RTCA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,585 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RTCA-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Cytosol to Golgi apparatus transport, and UDP-galactose transmembrane transport. Each is linked with RTCA in more than 16 cancer types. Because this analysis shows association rather than direction, both RTCA-to-partner and partner-to-RTCA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by RTCA-low versus RTCA-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTCA→partner) and Y-score (partner→RTCA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Zinc ion import into Golgi lumen →	+0.129	+0.796	<.001	<.001	3	17
KIDNEY	Cytosol to Golgi apparatus transport →	+0.147	+0.872	<.001	<.001	3	13
LUNG_SCLC	UDP-galactose transmembrane transport →	+0.168	+0.788	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Telomeric 3' overhang formation →	+0.146	+0.822	<.001	<.001	3	10
BLOOD_Myeloma	Positive regulation of centriole replication →	+0.130	+1.109	<.001	<.001	3	9
BLOOD_Leukemia	Myoblast migration involved in skeletal muscle regeneration →	+0.171	+0.550	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,585 associations by consensus.

Zinc ion import into Golgi lumen by RTCA expression — KIDNEY

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