RTBDN

Across TCGA patient cohorts, RTBDN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,100 significant associations in total. LGG shows the largest number of these associations.

The most reproducible RTBDN-associated GO terms across cancer lineages are Protein K6-linked ubiquitination, Synaptic vesicle membrane organization, and Double-strand break repair via break-induced replication. Each is linked with RTBDN in more than 14 cancer types. Because this analysis shows association rather than direction, both RTBDN-to-partner and partner-to-RTBDN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein K6-linked ubiquitination grouped by RTBDN-low versus RTBDN-high in PCPG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RTBDN→partner) and Y-score (partner→RTBDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	Protein K6-linked ubiquitination →	+0.047	+0.875	<.001	<.001	3	15
SCLC	Synaptic vesicle membrane organization →	+0.172	+0.998	<.001	<.001	3	13
SARC	Double-strand break repair via break-induced replication →	+0.057	+0.614	<.001	<.001	3	13
SCLC	Vesicle fusion to plasma membrane →	+0.168	+1.055	<.001	<.001	3	13
SARC	Establishment of spindle orientation →	+0.053	+0.675	<.001	<.001	3	12
LAML	Positive regulation of cell cycle G2/M phase transition →	+0.058	+0.139	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,100 associations by consensus.

Protein K6-linked ubiquitination by RTBDN expression — PCPG

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