RTBDN

Across TCGA patient cohorts, RTBDN protein abundance is significantly associated with the RNA expression of many other genes, with 3,644 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RTBDN-associated genes across cancer lineages are DNAL4, CHKB, and CHGA. Each is linked with RTBDN in more than 1 cancer types. Because this analysis shows association rather than direction, both RTBDN-to-partner and partner-to-RTBDN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RTBDN versus DNAL4 in BRCA, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RTBDN→partner) and Y-score (partner→RTBDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNAL4 →	+0.736	+2.943	.005	.004	3	1
BRCA	CHKB →	+0.787	+2.942	.003	.004	3	1
BRCA	CHGA →	+7.816	+3.873	<.001	.003	3	1
BRCA	SYP →	+4.553	+3.026	.002	.007	3	1
BRCA	AP3B2 →	+3.506	+3.173	<.001	.009	3	1
BRCA	MAG →	+2.103	+3.873	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,644 associations by consensus.

RTBDN vs DNAL4 — BRCA

Explore this scatter interactively →