RSU1

Across TCGA pan-cancer cohorts, RSU1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RSU1 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RSU1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RSU1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LSCC, and GBM are the cancer types where RSU1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.898	0.447	.008	24	view →
LSCC	OS	Quartile	II,III,IV	0.707	1.000	.006	12	view →
GBM	DFS	Median	All	0.281	0.459	.012	9	view →
UCEC	OS	Median	III,IV	0.322	0.915	.017	4	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	3	view →
HNSC	DFS	Tertile	II,III,IV	0.533	0.760	.036	2	view →
LUAD	DFS	Quartile	II,III,IV	0.785	0.980	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RSU1–CCRCC (DFS)

Open the CCRCC breakdown →