RSU1

Across TCGA patient cohorts, RSU1 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible RSU1-associated genes across cancer lineages are GMP, CMP, and Macrophages M2. Each is linked with RSU1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSU1-to-partner and partner-to-RSU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by RSU1-low versus RSU1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSU1→partner) and Y-score (partner→RSU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.037	+2.527	.004	.031	3	3
LUSC	CMP →	+0.023	+2.467	<.001	.018	3	2
LUSC	Macrophages M2 →	+0.032	+2.831	.009	.036	3	1
LUSC	Preadipocytes →	+0.016	+3.121	.003	.031	3	1
UCEC	Neutrophils →	+0.025	+2.488	<.001	.012	3	1
UCEC	Skeletal muscle →	+0.059	+3.010	.020	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GMP by RSU1 expression — LUSC

Explore this box plot interactively →