RSRC2

Across TCGA patient cohorts, RSRC2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RSRC2-associated genes across cancer lineages are ZCCHC8, CCDC59, and SNRPE. Each is linked with RSRC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both RSRC2-to-partner and partner-to-RSRC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RSRC2 versus ZCCHC8 in UCEC, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSRC2→partner) and Y-score (partner→RSRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZCCHC8 →	+0.346	+0.140	<.001	.001	3	7
HNSC	CCDC59 →	+0.580	+0.191	.008	.001	3	7
HNSC	SNRPE →	+0.864	+0.182	.001	<.001	3	7
OV	PPP1CC →	+0.469	+0.327	.001	<.001	3	7
HNSC	ZBTB12 →	+0.889	+0.221	<.001	<.001	3	7
HNSC	USP21 →	+0.556	+0.254	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,457 associations by consensus.

RSRC2 vs ZCCHC8 — UCEC

Explore this scatter interactively →