RSRC1

Across TCGA patient cohorts, RSRC1 mutation is significantly associated with the RNA expression of many other genes, with 3,037 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSRC1-associated genes across cancer lineages are RNA5SP158, RPS29P9, and MRPS21P2. Each is linked with RSRC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSRC1-to-partner and partner-to-RSRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP158 grouped by RSRC1-low versus RSRC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSRC1→partner) and Y-score (partner→RSRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP158 →	+0.201	+3.021	<.001	.009	3	3
COAD	RPS29P9 →	+0.810	+4.021	<.001	.006	3	2
COAD	MRPS21P2 →	+0.426	+3.870	<.001	.006	3	2
COAD	ATP5MGP7 →	+0.336	+5.020	<.001	<.001	3	2
LUAD	RPL7AP72 →	+0.077	+5.044	.003	.009	3	2
LUAD	TMEM97P2 →	+0.154	+5.984	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,037 associations by consensus.

RNA5SP158 by RSRC1 expression — SKCM

Explore this box plot interactively →