RSRC1

Across TCGA cell cohorts, RSRC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,637 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RSRC1-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Mitotic G2/M transition checkpoint, and Regulation of G2/M transition of mitotic cell cycle. Each is linked with RSRC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both RSRC1-to-partner and partner-to-RSRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome condensation grouped by RSRC1-low versus RSRC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RSRC1→partner) and Y-score (partner→RSRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of chromosome condensation →	+0.224	+0.653	.003	<.001	3	13
BLOOD_Myeloma	Mitotic G2/M transition checkpoint →	+0.086	+0.828	<.001	<.001	3	13
BLOOD_Myeloma	Regulation of G2/M transition of mitotic cell cycle →	+0.073	+0.920	<.001	<.001	3	12
PANCREAS	Double-strand break repair →	+0.057	+0.864	.003	.001	3	12
LUNG_NSCLC_LUSC	Alternative mRNA splicing, via spliceosome →	+0.136	+0.827	<.001	.002	3	12
PANCREAS	Mitotic sister chromatid cohesion →	+0.105	+0.773	.002	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,637 associations by consensus.

Positive regulation of chromosome condensation by RSRC1 expression — BONE

Explore this box plot interactively →