RSPO4

Across TCGA cell cohorts, RSPO4 RNA expression is significantly associated with the go_rna of many other GO terms, with 947 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible RSPO4-associated GO terms across cancer lineages are Potassium ion transport, Regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with RSPO4 in more than 7 cancer types. Because this analysis shows association rather than direction, both RSPO4-to-partner and partner-to-RSPO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transport grouped by RSPO4-low versus RSPO4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPO4→partner) and Y-score (partner→RSPO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Potassium ion transport →	-0.042	-0.711	<.001	.006	3	8
OVARY	Regulation of myoblast fusion →	+0.096	+1.378	<.001	.002	2	8
OVARY	Cytoplasmic translation →	+0.093	+1.549	<.001	<.001	2	8
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.099	+1.326	<.001	.008	2	8
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.089	+1.376	.001	.002	2	8
OVARY	Cell fate specification →	-0.067	-1.717	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 947 associations by consensus.

Potassium ion transport by RSPO4 expression — SKIN

Explore this box plot interactively →