RSPH3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RSPH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,775 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RSPH3-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Cilium or flagellum-dependent cell motility. Each is linked with RSPH3 in more than 16 cancer types. Because this analysis shows association rather than direction, both RSPH3-to-partner and partner-to-RSPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by RSPH3-low versus RSPH3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH3→partner) and Y-score (partner→RSPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaProcess utilizing autophagic mechanism →+0.060+1.116<.001.001317
BLOOD_MyelomaAutophagy →+0.060+1.116<.001.001317
UPPER_AERODIGESTIVE_TRACTCilium or flagellum-dependent cell motility →-0.121-0.880<.001<.001317
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.121-0.880<.001<.001317
UPPER_AERODIGESTIVE_TRACTCilium movement involved in cell motility →-0.123-0.832<.001.001317
STOMACHMacroautophagy →+0.085+1.376<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,775 associations by consensus.

Process utilizing autophagic mechanism by RSPH3 expression — BLOOD_Myeloma

Box plot of Process utilizing autophagic mechanism in RSPH3-low vs RSPH3-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration