RSPH10B2

Across TCGA patient cohorts, RSPH10B2 mutation is significantly associated with the RNA expression of many other genes, with 1,345 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RSPH10B2-associated genes across cancer lineages are RPL23AP40, OFD1P2Y, and PRUNEP1. Each is linked with RSPH10B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RSPH10B2-to-partner and partner-to-RSPH10B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP40 grouped by RSPH10B2-low versus RSPH10B2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B2→partner) and Y-score (partner→RSPH10B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP40 →	+0.119	+4.628	.004	.004	3	3
READ	OFD1P2Y →	+0.048	+6.257	<.001	.001	3	2
COAD	PRUNEP1 →	+0.125	+4.602	.004	.008	3	2
CESC	TRAJ12 →	+0.619	+4.193	.001	.009	3	2
LUSC	BPY2DP →	+0.139	+4.548	.002	.009	3	2
UCEC	RNA5SP423 →	+0.636	+1.824	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,345 associations by consensus.

RPL23AP40 by RSPH10B2 expression — SKCM

Explore this box plot interactively →