RSPH10B2

Across TCGA cell cohorts, RSPH10B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,474 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RSPH10B2-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Negative regulation of mRNA metabolic process. Each is linked with RSPH10B2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RSPH10B2-to-partner and partner-to-RSPH10B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by RSPH10B2-low versus RSPH10B2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RSPH10B2→partner) and Y-score (partner→RSPH10B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Epigenetic regulation of gene expression →	+0.052	+0.120	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.082	+0.137	<.001	.002	3	11
LIVER	Negative regulation of mRNA metabolic process →	+0.079	+0.094	<.001	<.001	3	10
STOMACH	Regulation of RNA splicing →	+0.063	+0.214	.006	.009	2	11
OVARY	Negative regulation of gene expression, epigenetic →	+0.059	+0.119	<.001	<.001	3	10
BLOOD_Lymphoma	Heterochromatin formation →	+0.058	+0.210	<.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,474 associations by consensus.

Epigenetic regulation of gene expression by RSPH10B2 expression — OVARY

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